A 62-year-old male with a past medical history of Barrett's esophagus, Chronic Lymphocytic Leukemia (CLL), and hyperlipidemia presents with intermittent left rib pain and worsening discomfort over the past 2 weeks, exacerbated by coughing and certain movements, after a recent upper respiratory infection, with a diagnosis of nondisplaced fractures of the anterior 5th, 6th, and 7th ribs, and has been taking Naprosyn (Naproxen) and Tylenol (Acetaminophen) for discomfort?

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Differential Diagnosis

  • Single most likely diagnosis
    • Costochondritis or rib fracture: The patient's history of forceful coughing and sneezing, followed by intermittent left rib pain that worsened over time, is consistent with a rib fracture or costochondritis. The patient's recent imaging showing nondisplaced anterior 5th, 6th, and 7th rib fractures supports this diagnosis.
  • Other Likely diagnoses
    • Musculoskeletal strain: The patient's symptoms of worsening discomfort with certain movements and coughing could also be consistent with a musculoskeletal strain.
    • Precordial catch syndrome: This condition is characterized by sharp, stabbing chest pain that can be exacerbated by movement or deep breathing, which could be considered given the patient's symptoms.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Pulmonary embolism: Although the patient denies shortness of breath or chest pain, a pulmonary embolism could present atypically, especially in a patient with a history of cancer (CLL).
    • Pneumonia or lung abscess: The patient's recent history of a cold/cough and current symptoms could be consistent with a pulmonary infection, which would require prompt treatment.
    • Cardiac ischemia or myocardial infarction: The patient's history of hyperlipidemia and current symptoms of chest discomfort could be consistent with cardiac ischemia or myocardial infarction, although the patient denies typical symptoms.
  • Rare diagnoses
    • Osteomyelitis or rib osteonecrosis: These conditions could present with similar symptoms, although they are less likely given the patient's history and lack of systemic symptoms such as fever.
    • Tietze's syndrome: This is a rare condition characterized by inflammation of the cartilages and surrounding tissues of the ribs, which could present with similar symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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