From the Guidelines
Changes in color vision are primarily caused by damage to the photoreceptors in the retina, which can be a result of various factors, including certain medications such as hydroxychloroquine and chloroquine 1.
Key Factors
- Medications: Hydroxychloroquine and chloroquine can cause toxicity to the retina, leading to damage to the photoreceptors and subsequent changes in color vision 1.
- Retinal damage: Damage to the inner and outer retina, as well as the retinal pigmented epithelium (RPE), can also contribute to changes in color vision 1.
- Diseases: Certain diseases, such as age-related macular degeneration (AMD), can cause progressive deterioration of the retina and lead to changes in color vision 1.
- Vascular occlusions: Central retinal artery occlusion (CRAO) can also cause sudden and painless monocular loss of visual acuity and peripheral vision, including impaired color vision 1.
Important Considerations
- Visual acuity: Impaired color vision is often proportional to visual acuity, with more severe visual loss resulting in greater impairment of color vision 1.
- Medication toxicity: The risk of medication toxicity, such as that caused by hydroxychloroquine and chloroquine, can be mitigated with regular screening and monitoring 1.
From the Research
Causes of Changes in Color Vision
There are no research papers to assist in answering this question, as the provided studies focus on colorectal cancer treatment and do not address color vision.
- The studies 2, 3, 4, 5, 6 discuss various treatments for colorectal cancer, including chemotherapy, ferroptosis, aflibercept, and immunotherapy, but do not mention color vision.
- None of the studies provide information on the causes of changes in color vision, suggesting that a different set of research papers would be needed to answer this question.