Sensory Nerves of the Arm
The arm receives sensory innervation from terminal branches of the brachial plexus (C5-T1), primarily through the lateral antebrachial cutaneous nerve (from the musculocutaneous nerve), medial antebrachial cutaneous nerve (from C8-T1 roots), and posterior antebrachial cutaneous nerve (from the radial nerve), with the median and ulnar nerves providing sensory coverage to the hand. 1, 2, 3
Brachial Plexus Origin
- The brachial plexus forms from ventral rami of C5-T1 spinal nerve roots, with occasional contributions from C4 and/or T2 1, 3
- This plexus provides both motor and sensory innervation to the entire upper extremity through its terminal branches 1
Major Sensory Nerves of the Forearm
Lateral Antebrachial Cutaneous Nerve
- This nerve is a purely sensory terminal branch of the musculocutaneous nerve, arising from the lateral cord of the brachial plexus 2, 4
- The anterior branch innervates 26% of the medial anterior forearm and 38.21% of the lateral anterior forearm 5
- The posterior branch covers 24.46% of the lateral posterior forearm 5
- Traumatic avulsion of C5-C7 roots is the primary mechanism causing injury to this nerve 2, 4
Medial Antebrachial Cutaneous Nerve
- Arises directly from the C8-T1 roots of the brachial plexus 2
- The anterior branch innervates 27.67% of the medial aspect of the anterior forearm 5
- The posterior branch covers 7.67% of the anterior region and 34.75% of the posterior region 5
Posterior Antebrachial Cutaneous Nerve
Hand Sensory Distribution
Median Nerve
- Provides cutaneous sensation to the palmar surface of the thumb, index finger, middle finger, and lateral half of the ring finger 3
- Originates from both lateral and medial cords of the brachial plexus 3
Ulnar Nerve
- Originates from the medial cord, derived from the lower trunk (C8-T1 roots) 3
- Supplies sensation to the little finger and medial half of the ring finger 3
Clinical Significance
Anatomical Landmarks
- A distinctive "drug line" (Voigt-Futcher line) on the upper arm marks the precise border between lateral and medial sensory innervation territories 6
- This line becomes clinically apparent during morbilliform drug eruptions and demonstrates the segmental nature of cutaneous sensory innervation 6
Nerve Coaptations
- Anastomoses exist between branches of the lateral, medial, and posterior antebrachial cutaneous nerves 5
- The middle third of the medial and lateral forearm contains the relatively densest total nerve branch distribution 5
Injury Patterns
- Complete brachial plexus lesions result in weakness, sensory loss, and flaccid loss of tendon reflexes throughout the C5-T1 distribution 1, 3
- Lower trunk injuries (C8-T1) primarily affect ulnar nerve function, leading to deficits in intrinsic hand sensation and motor control 3
- Electrodiagnostic studies confirm the clinical diagnosis of plexopathy and help differentiate it from radiculopathy 1, 4
Perioperative Considerations
- Limiting arm abduction to ≤90° in supine patients reduces the risk of brachial plexus and sensory branch injuries 2
- Position the arm in abduction on an arm-rest with the forearm in supination or neutral position to protect the lateral antebrachial cutaneous nerve 2
- Perform periodic checks of upper-extremity positioning during procedures to avoid excessive stretch or compression 2
Diagnostic Imaging
- MRI of the brachial plexus demonstrates 84% sensitivity and 91% specificity for detecting traumatic root avulsions 2, 4
- MR neurography with T2-weighted sequences is the reference technique for evaluating peripheral nerve pathology 2
- High-resolution ultrasound provides 77-79% sensitivity and 94-98% specificity as a bedside alternative 2