What is a Knee Fabella?
The fabella is a sesamoid bone embedded within the lateral head of the gastrocnemius muscle tendon, located behind the lateral femoral condyle in the posterolateral aspect of the knee. 1
Anatomical Characteristics
- The fabella sits within the gastrocnemius tendon close to the lateral femoral condyle and is connected to the fabellofibular ligament 2
- It often articulates directly with the lateral femoral condyle 3
- This is a normal anatomical variant, not a pathological finding 2
Prevalence Patterns
- Global prevalence: Approximately 36.80% of knees have ossified fabellae detectable by dissection, though this varies significantly by region 1
- Regional variation: Highest prevalence in Asia (48.6% in Chinese population), followed by Oceania, South America, Europe, Middle East, North America, and lowest in Africa 1, 4
- Gender distribution: Fabellae are 2.47-2.60% more common in men than women 1
- Bilateral presentation: Approximately 72.94% of cases are bilateral (present in both knees), and among unilateral cases, there is equal distribution between right and left knees 1
Age-Related Considerations
- Fabella prevalence increases with age, with ossification occurring either early (around 12 years old) or late in life (particularly increasing after 70 years old) 1
- Fabellar degeneration grades correlate with both advancing age and knee osteoarthritis severity 4
Clinical Significance
- Fabella syndrome: Can cause posterolateral knee pain due to biomechanical pressure of the fabella against the lateral femoral condyle 2
- Associated pathologies: May lead to common fibular nerve palsy, semimembranosus impingement, and can serve as an origin point for anomalous ligamentous bands 5, 3
- Osteoarthritis relationship: Fabellar degeneration grades are strongly correlated with knee osteoarthritis scores (r = 0.6892) 4
Diagnostic Approach
- Plain lateral knee radiographs readily identify ossified fabellae 4
- MRI should be obtained in patients with posterior knee pain without trauma history and normal plain radiographs to assess for fabella-related impingement or anomalous bands 5