When to Start Oral Nutritional Supplements (ONS)
Start oral nutritional supplements when a patient is malnourished or at nutritional risk and dietary counseling alone fails to meet nutritional requirements, but before progressing to more invasive enteral or parenteral nutrition.
Stepwise Approach to Initiating ONS
Step 1: Identify Patients Who Need Nutritional Intervention
- Begin ONS in patients who are malnourished or at risk of malnutrition when it would benefit outcomes or quality of life 1
- Evaluate nutritional status before considering any specialized nutrition support 1
Step 2: Optimize Oral Intake First
- First-line intervention: Improve the nutritional value of regular food and tailor intake to patient preferences, abilities, and schedule 1
- Provide dietary counseling as the initial approach 2
Step 3: Add ONS When Oral Intake Remains Inadequate
- When dietary counseling and food optimization alone are insufficient to meet nutritional requirements, add oral nutritional supplements 2, 1
- This represents the second tier of nutritional intervention before considering tube feeding 2
Step 4: Progress to More Invasive Routes Only If ONS Fails
- If oral nutrition remains inadequate despite counseling and ONS, then recommend enteral nutrition (EN) via feeding tube 2
- Use parenteral nutrition (PN) only if EN is not sufficient or feasible 2
Specific Clinical Contexts
Cancer Patients
- In cancer patients unable to maintain adequate oral intake, use the hierarchical approach: counseling → ONS → EN → PN 2
- The risks of PN outweigh benefits for patients with prognosis fewer than two months 2
Perioperative Patients
- Start ONS both preoperatively (from time of surgical decision until 1 day before surgery) and postoperatively (when able to take free fluids, continuing 4 weeks post-discharge) for lower gastrointestinal surgery 3
- Perioperative supplementation significantly reduces postoperative weight loss and minor complications 3
Elderly Post-Discharge Patients
- Initiate ONS immediately after hospital discharge in malnourished elderly patients (≥60 years) 4
- Continue for at least 3 months with energy and protein-enriched diet, calcium-vitamin D supplementation, and telephone counseling 4
- This approach decreases functional limitations and increases body weight 4
Critical Precautions
Refeeding Syndrome Risk
- If oral intake has been severely decreased for a prolonged period, increase nutrition (oral, enteral, or parenteral) slowly over several days 2
- Supplement with vitamin B1 at 200-300 mg daily before and during nutritional repletion 2
- Monitor and replace potassium (~2-4 mmol/kg/day), phosphate (0.3-0.6 mmol/kg/day), and magnesium (0.2 mmol/kg/day IV or 0.4 mmol/kg/day orally) 2
Patient Involvement
- Tailor the ONS prescription together with the patient, obtaining their acceptance as a prerequisite 5
- Be flexible regarding products and amounts prescribed based on patient preferences 5
Common Pitfall to Avoid
Do not bypass dietary counseling and ONS by jumping directly to tube feeding or parenteral nutrition unless there is a clear contraindication to the oral route (such as impaired swallowing safety or gastrointestinal dysfunction) 2, 1. The principle is to use the least invasive nutritional route that can meet the patient's needs.