What is the cause of numbness in my lower left lip?

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Last updated: April 27, 2025View editorial policy

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Differential Diagnosis for Numbness in the Lower Left Lip

  • Single most likely diagnosis
    • Trauma or injury to the lower lip: This is the most likely cause of numbness in the lower left lip, as it can result from a blow to the face, a fall, or other forms of physical trauma that damage the nerves.
  • Other Likely diagnoses
    • Dental problems (e.g., abscess, infection): Dental issues can cause numbness or tingling in the lip due to the proximity of the teeth and gums to the nerves that supply the lip.
    • Nutritional deficiencies (e.g., vitamin B12 deficiency): Certain nutritional deficiencies can cause numbness or tingling sensations in various parts of the body, including the lips.
    • Multiple sclerosis: This chronic autoimmune disease can cause numbness or tingling sensations in different parts of the body, including the face and lips.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Stroke or transient ischemic attack (TIA): Although less common, numbness in one part of the face can be a symptom of a stroke or TIA, which requires immediate medical attention.
    • Lyme disease: In rare cases, Lyme disease can cause numbness or tingling sensations in the face, including the lips.
    • Sjögren's syndrome: This autoimmune disorder can cause numbness or tingling sensations in the face, among other symptoms.
  • Rare diagnoses
    • Sarcoidosis: This rare disease can cause numbness or tingling sensations in various parts of the body, including the face and lips.
    • Leprosy: Also known as Hansen's disease, leprosy can cause numbness or tingling sensations in the skin, including the face and lips.
    • Trigeminal neuralgia: This rare condition affects the trigeminal nerve, which supplies sensation to the face, and can cause numbness, tingling, or pain in the lips and other parts of the face.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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