How many milliliters are in a typical clindamycin 1% topical gel bottle for acne?

Clindamycin Gel Bottle Size

Clindamycin phosphate 1% topical gel for acne is typically supplied in 30 mL, 60 mL, and 75 mL bottles, with 60 mL being a common dispensing size. 1

Standard Formulation Details

The FDA-approved formulation contains clindamycin phosphate equivalent to 10 mg clindamycin per milliliter (1% concentration) in various topical preparations including gel, solution, and lotion forms. 1

Available Package Sizes

• 60 mL bottles are documented as a standard supply size 1
• The concentration remains consistent at 1% (10 mg/mL) across all formulations 1
• Both gel and lotion formulations are available in this concentration 1

Clinical Application Context

The dosing recommendation is to apply a thin film once daily to affected areas, which means a 60 mL bottle provides approximately 60 days of treatment when using 1 mL per application. 2 This once-daily application has been shown to be as effective as twice-daily regimens in clinical trials. 3, 4

Important Prescribing Considerations

• Clindamycin should not be used as monotherapy due to bacterial resistance concerns 2
• Always combine with benzoyl peroxide to prevent antibiotic resistance development 2
• The medication is pregnancy category B and has not been established as safe in children under 12 years 2