What is the recommended management when a proton‑pump inhibitor (PPI) fails to control gastroesophageal reflux symptoms?

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Related Questions

What is the next step if a proton‑pump inhibitor (PPI) fails to relieve symptoms?
In a 55-year-old man with chronic gastroesophageal reflux disease, persistent heartburn despite two months of over-the-counter proton-pump inhibitor therapy, no dysphagia, odynophagia, bloating, or weight loss, a 20-pack-year smoking history (quit five years ago), obesity (BMI 32) and normal vital signs, what is the most appropriate next step in evaluation?
In a patient who has never taken a proton‑pump inhibitor and has severe reflux symptoms without internal scarring or damage, should surgery be recommended or should a trial of proton‑pump inhibitor therapy be initiated?
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What are the next steps if a proton‑pump inhibitor (PPI) fails to relieve reflux symptoms?

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