From the Guidelines
Ornidazole is indicated for the treatment of trichomoniasis and other infections, but its use is not mentioned in the provided guideline for the treatment of sexually transmitted diseases in Taiwan 1.
Indications and Timing
- The guideline does recommend metronidazole or tinidazole for the treatment of trichomoniasis, with a dose of 2g in a single dose or 500mg twice daily for 7 days 1.
- However, based on general medicine knowledge, ornidazole can be used as an alternative to metronidazole for the treatment of trichomoniasis, with a similar dose and duration.
- The timing of ornidazole use would depend on the specific infection being treated, but it is typically administered for 5-10 days, depending on the severity of the infection.
- It is essential to note that the use of ornidazole should be guided by local resistance patterns and treatment guidelines, as well as patient-specific factors such as allergy history and pregnancy status 1.
From the Research
Indications for Ornidazole
- Trichomoniasis: Ornidazole is effective in treating trichomoniasis, a protozoal infection caused by Trichomonas vaginalis 2.
- Giardiasis: Ornidazole is used to treat giardiasis, an intestinal infection caused by Giardia intestinalis 2, 3.
- Amebiasis: Ornidazole is effective in treating amebiasis, a protozoal infection caused by Entamoeba histolytica 2.
- Anaerobic infections: Ornidazole may be used to treat anaerobic bacterial infections, although metronidazole is more commonly used for this indication 4.
Timing and Dosage of Ornidazole
- Single-dose or once-daily administration: Ornidazole has a longer half-life than metronidazole, allowing for single-dose or once-daily administration 2, 3.
- Giardiasis treatment: A single oral dose of 1.5 g of ornidazole is effective in treating giardiasis, with parasites disappearing from feces within 2-3 days and symptoms subsiding within 5 days 3.
- Trichomoniasis treatment: The dosage and timing of ornidazole for trichomoniasis treatment are not specified in the provided studies, but it is likely similar to that of metronidazole or other nitroimidazoles 2, 4.