From the Research
Uses of Calcium Dobesilate
The uses of Calcium Dobesilate can be summarized as follows:
- Treatment of Chronic Venous Insufficiency (CVI) symptoms, such as edema, night cramps, and discomfort 1, 2, 3
- Improvement of quality of life in patients with CVI, particularly in those with advanced disease 1, 2, 3
- Reduction of microvascular permeability and improvement of visual acuity in diabetic retinopathy patients 4, 5
- Treatment of micro-vascular damage-related diseases, such as diabetic nephropathy (DN) and diabetic retinopathy (DR) 4
- Antioxidant and vascular protective effects, which may contribute to its therapeutic benefits 4, 5
Specific Applications
Some specific applications of Calcium Dobesilate include:
- Management of CVI symptoms, such as pain, heaviness, and malleolar swelling, particularly in severe cases 3
- Improvement of paresthesias and reduction of leg volume in patients with severe CVI 3
- Slowdown of the progression of diabetic retinopathy after long-term oral treatment 5
- Preservation of vascular endothelial function by acting as an antioxidant to protect lipids from peroxidation 5