Can Oseltamivir (Tamiflu) be administered rectally?

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Last updated: February 17, 2025View editorial policy

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From the Research

Administration of Oseltamivir

  • The provided studies do not mention the administration of Oseltamivir (Tamiflu) via the rectal route 1, 2, 3, 4, 5.
  • Oseltamivir is typically administered orally, in the form of a prodrug that is rapidly converted into the active metabolite oseltamivir carboxylate 3.
  • In some cases, oseltamivir can be administered intravenously, particularly in patients with severe influenza virus infection requiring organ replacement therapy 2.
  • There is no evidence to suggest that rectal administration of oseltamivir is a recommended or studied route of administration.

Routes of Administration

  • Oral administration: Oseltamivir is commonly administered orally, with a recommended dosage of 75 mg twice daily for 5 days 1, 4.
  • Intravenous administration: Oseltamivir can be administered intravenously in certain cases, such as in patients with severe influenza virus infection requiring organ replacement therapy 2.
  • No mention of rectal administration: None of the provided studies mention the administration of oseltamivir via the rectal route 1, 2, 3, 4, 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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