What is the association between resolved low-lying placentation (placenta previa) and the risk of postpartum hemorrhage (PPH)?

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Last updated: February 17, 2025View editorial policy

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From the Guidelines

Resolved low-lying placentation is associated with an increased risk of postpartum hemorrhage (PPH). The evidence suggests that women with a history of low-lying placentation, including placenta previa, are at a higher risk of developing PPH 1.

Key Risk Factors

  • Previous cesarean delivery: The incidence of placenta accreta spectrum, which is a significant risk factor for PPH, increases with the number of prior cesarean deliveries 1.
  • Placenta previa: The risk of placenta accreta spectrum is dramatically increased in women with placenta previa and one or more previous cesarean deliveries 1.
  • Advanced maternal age and multiparity: These factors also increase the risk of placenta accreta spectrum and subsequent PPH 1.

Management Implications

  • Increased vigilance: Women with a history of low-lying placentation should be closely monitored for signs of PPH during the postpartum period 1.
  • Prophylactic oxytocin administration: Consider administering oxytocin (10-20 units) during the third stage of labor to reduce the risk of PPH in these women 1.
  • Availability of blood transfusion protocols: Ensure that women with a history of low-lying placentation have access to a blood bank capable of employing massive transfusion protocols in case of severe PPH 1.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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