Bell's Palsy Treatment
Prescribe oral corticosteroids (prednisolone 60 mg daily for 5 days, then taper over 5 days, OR prednisolone 50 mg daily for 10 days) within 72 hours of symptom onset for all patients 16 years and older with Bell's palsy. 1
Primary Treatment Algorithm
Adults (≥16 years)
Corticosteroids are mandatory - This is a strong recommendation based on high-quality RCTs showing 83% recovery at 3 months with steroids versus 63.6% with placebo (p<0.001), and 94.4% versus 81.6% at 9 months 1. The evidence demonstrates clear benefit in both recovery time and final functional outcomes.
Dosing regimens (choose one):
- Prednisolone 60 mg daily × 5 days, then taper over 5 days
- Prednisolone 50 mg daily × 10 days (25 mg twice daily)
- Prednisone 60 mg daily × 5 days with 5-day taper 1
Timing is critical: Initiate within 72 hours of symptom onset. Benefit after 72 hours is unclear 1.
Antiviral Therapy Decision
Do NOT use antivirals alone - This is strongly contraindicated as monotherapy provides no benefit over placebo 1.
Consider adding antivirals to steroids in these specific situations:
- Complete facial paralysis (severe disease) 1, 2
- Early presentation within 72 hours
- Ramsay-Hunt syndrome (herpes zoster involvement) 2
Antiviral options (if used with steroids):
The evidence for combination therapy is mixed - some smaller trials showed improvement (96.5% vs 89.7% recovery), but larger high-quality trials showed no significant benefit 1. The guideline rates this as an "option" rather than a recommendation, meaning equilibrium of benefit and harm 1.
Pediatric Patients (<16 years)
Steroids may be considered but are not mandatory - Children have spontaneous recovery rates up to 90%, higher than adults 1. No controlled trials support routine steroid use in children 1. If treating, use similar dosing adjusted for weight with significant caregiver involvement in decision-making 1.
Essential Supportive Care
Eye protection is mandatory for patients with impaired eye closure 1:
- Artificial tears during the day
- Lubricating ointment at night
- Eye taping or patching if needed
- Immediate ophthalmology referral if ocular symptoms develop
What NOT to Do
Avoid routine testing 1:
- No routine laboratory tests (unless Lyme disease endemic area - then check Lyme serology)
- No routine imaging at initial diagnosis
- No electrodiagnostic testing for incomplete paralysis
No recommendation for 1:
- Surgical decompression
- Acupuncture
- Physical therapy (though may consider in severe paralysis 3)
Follow-Up Requirements
Reassess or refer to facial nerve specialist if 1:
- New or worsening neurologic findings at any point
- Ocular symptoms developing at any point
- Incomplete facial recovery at 3 months
Red flags requiring imaging (MRI with gadolinium of entire facial nerve course) 1:
- Recurrent paralysis on same side
- Isolated branch paralysis
- Other cranial nerve involvement
- Bilateral facial palsy
- History of trauma or tumor
- No recovery signs after 3 months
Common Pitfalls
The 72-hour window is real - While some recent data suggests flexibility 4, the strongest evidence supports early initiation. Don't delay treatment waiting for "confirmation" - Bell's palsy is a clinical diagnosis of exclusion.
Don't confuse "may offer" with "should offer" - The guideline language for antivirals is deliberately weak ("option" with "equilibrium of benefit and harm") 1. Steroids alone are the evidence-based standard.
Pregnancy considerations - Pregnant women have up to 90% spontaneous recovery rates 3. Steroids remain appropriate, but the risk-benefit discussion is particularly important given higher baseline recovery rates.
Severity matters for antiviral decisions - If considering combination therapy, reserve it for complete paralysis cases where some evidence suggests potential benefit 1, 2, 4.