What is the purpose of Preparation H (phenylephrine)

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Preparation H should be used with caution and under the guidance of a healthcare provider, as the most recent and highest quality study suggests that polidocanol sclerotherapy may be associated with higher therapeutic success in patients with symptomatic grade I-III internal hemorrhoids 1.

Overview of Preparation H

Preparation H is an over-the-counter medication primarily used to treat hemorrhoids. It comes in various forms including creams, ointments, suppositories, and wipes. For hemorrhoid relief, apply Preparation H up to four times daily, especially after bowel movements. The standard cream or ointment should be applied externally to the affected area, while suppositories are designed for internal hemorrhoids. Most formulations contain ingredients like phenylephrine (a vasoconstrictor that shrinks swollen tissue), mineral oil (for lubrication), and sometimes witch hazel (for soothing properties).

Important Considerations

  • Treatment duration should typically not exceed 7 consecutive days unless directed by a healthcare provider.
  • If symptoms persist beyond a week, consult a doctor as this may indicate a more serious condition.
  • Preparation H works by temporarily reducing swelling, providing pain relief, and protecting irritated tissue.
  • While effective for temporary relief, addressing underlying causes of hemorrhoids such as constipation, straining during bowel movements, and inadequate fiber intake is important for long-term management.
  • Recent studies suggest that office-based procedures like rubber band ligation and sclerotherapy may be effective in managing hemorrhoidal disease, with polidocanol sclerotherapy showing promising results 1.
  • However, these procedures should be performed under the guidance of a healthcare provider, as they may be associated with complications such as pain, bleeding, and infection 2, 3.

Key Takeaways

  • Preparation H can be used for temporary relief of hemorrhoid symptoms.
  • Office-based procedures like polidocanol sclerotherapy may be associated with higher therapeutic success in patients with symptomatic grade I-III internal hemorrhoids.
  • It is essential to address underlying causes of hemorrhoids for long-term management.
  • Healthcare provider guidance is crucial when using Preparation H or undergoing office-based procedures for hemorrhoid treatment.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.