Is minoxidil (Rogaine) safe to use in patients with glaucoma?

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Last updated: April 28, 2025View editorial policy

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From the Research

Minoxidil can be used in glaucoma patients, but with caution and close monitoring, as the current evidence suggests that topical minoxidil has minimal systemic absorption and does not typically affect intraocular pressure, although oral minoxidil may require more careful consideration due to potential fluid retention and drug interactions 1.

Key Considerations

  • Topical minoxidil is generally considered safe for most glaucoma patients, with minimal systemic absorption and no significant impact on intraocular pressure 1.
  • Oral minoxidil, used for treating high blood pressure, may cause fluid retention, which could indirectly affect some types of glaucoma, and its use in glaucoma patients requires careful evaluation of potential drug interactions 2.
  • The safety profile of minoxidil in glaucoma patients depends on the specific type of glaucoma, its severity, and whether it is well-controlled 3.

Recommendations

  • Glaucoma patients should consult with both their ophthalmologist and the prescribing physician before using minoxidil to ensure the medication will not adversely affect their eye condition 1.
  • Regular eye pressure monitoring may be recommended when starting minoxidil treatment to ensure no negative effects occur 4.
  • Patients with glaucoma should be aware of the potential risks and benefits of minoxidil and discuss any concerns with their healthcare provider, considering the most recent and highest quality evidence available 1.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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