From the Research
Moringa oleifera may be a beneficial complementary treatment for liver disease, particularly for Metabolic Associated Fatty Liver Disease (MAFLD), as it has been shown to improve insulin resistance, de novo lipogenesis, hepatic inflammation, and ER stress, as demonstrated in a 2022 study 1.
Key Findings
- The 2022 study found that Moringa oleifera aqueous extract improved MAFLD by inducing epigenetic modifications, reducing inflammatory nodules, macro steatosis, fibrosis, collagen, and αSMA reactivity in a model of nonalcoholic steatohepatitis (NASH) 1.
- Another study published in 2021 isolated compounds from Moringa oleifera that regulated NAFLD, including 1-hydroxy-3-phenylpropan-2-yl benzoate, which had a concentration-dependent inhibitory effect on intracellular lipid accumulation induced by stimulation of linoleic acid (LA) 2.
- However, it is essential to note that while moringa may offer some benefits, it should not replace conventional medical treatment for liver disease.
Considerations for Use
- Patients with liver disease should consult their healthcare provider before using moringa, especially if taking medications, as potential interactions may occur.
- Moringa should be used alongside, not instead of, prescribed treatments for liver disease, and patients should inform their doctors about any supplements they're taking.
- Those with hormone-sensitive conditions should exercise caution as moringa may have mild estrogenic effects.
Dosage and Preparation
- Moringa can be consumed as a powder (1-2 teaspoons daily), capsules (400-500mg 1-3 times daily), or as tea.
- The protective effects of moringa are attributed to compounds like quercetin, chlorogenic acid, and vitamin C, which help neutralize free radicals and reduce oxidative stress in the liver.