What is the brand name of the 52 mg levonorgestrel-releasing intrauterine device (LNG‑IUD)?

Brand Names for 52 mg LNG-IUD

The 52 mg levonorgestrel-releasing intrauterine device (LNG-IUD) is available under two brand names: Mirena and Liletta. 1, 2

Key Distinguishing Features

Both devices contain the same 52 mg dose of levonorgestrel, but differ in their FDA-approved duration of use:

• Mirena: Approved for 5 years of use 1, 2, though clinical data demonstrate continued contraceptive efficacy for up to 7-8 years 1, 3
• Liletta: Initially approved for 3 years 1, though this may have been updated since the 2016 guideline publication

Clinical Context

The 52 mg LNG-IUD represents the higher-dose formulation compared to:

• Skyla: 13.5 mg levonorgestrel (approved for 3 years) 1, 2
• Kyleena: 19.5 mg levonorgestrel 4

Both Mirena and Liletta provide highly effective contraception with failure rates less than 1% 1, 2 and offer additional benefits including reduced menstrual bleeding, with many users experiencing amenorrhea over time 1. The devices are appropriate for adolescents and nulliparous women 1, 2.

Important note: The levonorgestrel tablet referenced in the drug label 5 is a completely different product—this is emergency contraception (1.5 mg oral tablet), not an intrauterine device.