What is the differential diagnosis and recommended workup for a 30-year-old female with acute neck and shoulder pain, stiffness, and limited range of motion, who has been taking Flexeril (cyclobenzaprine) 5mg and meloxicam 7.5mg, following a recent inciting event of prolonged neck rotation?

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Differential Diagnosis for a 30-year-old Female with Neck and Shoulder Pain

Single Most Likely Diagnosis

  • Muscle Strain: The patient's history of turning her neck to the left for too long during a stretch and the subsequent onset of neck and shoulder pain suggests a muscle strain. The improvement with muscle relaxers and the localized nature of the pain also support this diagnosis.

Other Likely Diagnoses

  • Cervical Facet Joint Pain: The patient's pain is exacerbated by movement, particularly turning her head up, which could indicate facet joint involvement. The fact that she has some range of motion but experiences pain, especially when moving her neck, supports this possibility.
  • Cervical Disc Herniation: Although less likely given the acute onset and the absence of arm pain, a cervical disc herniation could still be considered, especially if the pain persists or worsens despite conservative management.
  • Thoracic Outlet Syndrome: The patient's complaint of pain in the neck and right shoulder could suggest thoracic outlet syndrome, although the absence of arm pain or paresthesia makes this less likely.

Do Not Miss Diagnoses

  • Cervical Spine Fracture: Although the patient had a normal CT scan after a car accident a year ago, any new trauma or significant force applied to the neck (like the described stretching incident) could potentially lead to a fracture, especially if the patient has underlying osteoporosis or another condition affecting bone density.
  • Meningitis: While the patient does not exhibit typical symptoms like fever or headache, meningitis can present atypically, and neck stiffness is a key symptom. Given the potential severity of this condition, it should be considered, especially if the patient's condition worsens or if other concerning symptoms develop.
  • Spinal Epidural Abscess: This is a rare but serious condition that could present with neck pain and stiffness. It is more likely in immunocompromised patients or those with a history of intravenous drug use, but it should be considered in any patient with severe or worsening neck pain.

Rare Diagnoses

  • Rheumatological Conditions: Conditions like rheumatoid arthritis or ankylosing spondylitis could present with neck and shoulder pain, although they are less likely given the patient's age and the acute onset of symptoms.
  • Tumors: Both primary and metastatic tumors of the spine can cause neck and shoulder pain. While rare, they should be considered, especially if the patient has a history of cancer or if the pain does not respond to conservative management.

Recommended Workup Tests

  • X-rays of the Cervical Spine: To evaluate for fractures, degenerative changes, or other bony abnormalities.
  • MRI of the Cervical Spine: If there is suspicion of a herniated disc, spinal stenosis, or other soft tissue abnormalities.
  • EMG/NCS (Electromyography/Nerve Conduction Studies): If there is suspicion of nerve root impingement or other neurological conditions.
  • Blood Tests: To evaluate for inflammatory markers if a rheumatological condition is suspected.
  • CT Scan: If an MRI is not available or if there is a need for better visualization of bony structures.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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