Which virus lacks DNA polymerase in its virion: HTLV (Human T-lymphotropic virus), HIV (Human Immunodeficiency Virus), EBV (Epstein-Barr Virus), or HBV (Hepatitis B Virus)?

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From the Research

Virus Characteristics

  • HTLV (Human T-lymphotropic virus) is a retrovirus that contains reverse transcriptase in its virion 1, 2.
  • HIV (Human Immunodeficiency Virus) is also a retrovirus with reverse transcriptase in its virion 1, 3, 4, 2.
  • EBV (Epstein-Barr Virus) is a DNA virus and does not require reverse transcriptase for its replication.
  • HBV (Hepatitis B Virus) is a DNA virus, but it replicates through an RNA intermediate and contains a reverse transcriptase-like enzyme in its virion 4.

Reverse Transcriptase in Virions

  • Retroviruses, including HTLV and HIV, have reverse transcriptase in their virions 1, 3, 4, 2.
  • HBV, a member of the Hepadnaviridae family, also contains a reverse transcriptase-like enzyme in its virion 4.
  • There is no evidence to suggest that EBV lacks DNA polymerase in its virion, but rather it is a DNA virus that does not require reverse transcriptase for replication.

Conclusion Drawn from Evidence

Based on the provided evidence, it appears that EBV (Epstein-Barr Virus) is the virus that lacks reverse transcriptase (an RNA-dependent DNA polymerase) in its virion, as it is a DNA virus and does not require this enzyme for replication 1, 3, 4, 2.

References

Research

Human retroviruses in leukaemia and AIDS: reflections on their discovery, biology and epidemiology.

Biological reviews of the Cambridge Philosophical Society, 2004

Research

Retroviral reverse transcriptase: synthesis, structure, and function.

Journal of acquired immune deficiency syndromes, 1990

Research

Viral reverse transcriptases.

Virus research, 2017

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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