What is the cause of a 48-year-old female's chronic abdominal pain, characterized by intermittent left and right upper quadrant pain, worsened by eating, with a history of Gastroesophageal Reflux Disease (GERD), constipation, Helicobacter Pylori (H. Pylori) infection, and a body mass index (BMI) of 31.25, currently experiencing bloating and constipation, with a recent diagnosis of a possible endometrial polyp?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Maria's Chronic Abdominal Pain

Single Most Likely Diagnosis

  • Irritable Bowel Syndrome (IBS): This diagnosis is likely due to Maria's symptoms of intermittent abdominal pain, bloating, gas buildup, and altered bowel habits (constipation and occasional diarrhea). Her pain worsening with eating and improvement with bowel movements also supports this diagnosis.

Other Likely Diagnoses

  • Gastroesophageal Reflux Disease (GERD) exacerbation: Given Maria's history of GERD, her symptoms of abdominal pain, especially after eating, could be related to GERD exacerbation, possibly due to her diet (sodas, spicy food, coffee).
  • Constipation: Maria's reported constipation, straining during bowel movements, and irregular bowel habits could contribute to her abdominal pain.
  • Endometrial polyp: Although less directly related to her gastrointestinal symptoms, the possible endometrial polyp found on her transvaginal ultrasound could be contributing to her abdominal pain, especially considering her upcoming gynecology appointment.

Do Not Miss Diagnoses

  • Pancreatitis: Although less likely, pancreatitis could cause intermittent abdominal pain radiating to the mid-back, worsened by eating. It's crucial to consider this diagnosis due to its potential severity.
  • Gallbladder disease: Given Maria's symptoms of right upper quadrant pain and worsening pain after eating, gallbladder disease (e.g., cholecystitis or gallstones) should be considered.
  • Inflammatory bowel disease (IBD): Conditions like Crohn's disease or ulcerative colitis could present with chronic abdominal pain, changes in bowel habits, and other symptoms Maria is experiencing.

Rare Diagnoses

  • Celiac disease: An autoimmune reaction to gluten could cause abdominal pain, bloating, and changes in bowel habits, although this would be less common.
  • Small intestine bacterial overgrowth (SIBO): This condition, characterized by an overgrowth of bacteria in the small intestine, could lead to symptoms similar to IBS, including bloating, gas, and abdominal pain.
  • Abdominal wall pain: Sometimes, abdominal pain can be referred from the abdominal wall itself, due to conditions like abdominal wall hernias or myofascial pain syndrome, although these would be less likely given Maria's other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.