What is the dosage of Motilium (Domperidone) syrup for pediatric patients?

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Last updated: April 29, 2025View editorial policy

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From the Research

Motilium (domperidone) syrup dosage for children should be limited to 0.25-0.5 mg/kg of body weight, given three to four times daily before meals, with a maximum daily dose not exceeding 2.5 mg/kg or 80 mg total per day, due to concerns about cardiac side effects, as reported in the most recent study 1. The dosage of Motilium syrup for kids is a critical consideration, given the potential risks associated with its use.

  • The recommended dosage is typically in the range of 0.25-0.5 mg/kg of body weight, given three to four times daily before meals.
  • For example, a 20 kg child would receive 5-10 mg per dose.
  • Treatment duration should generally be limited to one week, as prolonged use may increase the risk of cardiac side effects.
  • It's essential to note that domperidone is not approved for use in children in many countries, including the United States, due to concerns about cardiac side effects, as highlighted in the study 2.
  • Before giving this medication to a child, parents should always consult with a healthcare provider, as there are significant safety concerns, particularly regarding heart rhythm abnormalities, and alternative medications may be more appropriate depending on the child's specific condition and medical history, as discussed in the study 3.
  • The most recent study 1 provides an overview of the efficacy and safety profile of domperidone for the treatment of GI disorders in infants and children, which is essential for making informed decisions about its use.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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