Management of Blood Blisters
For simple blood blisters (traumatic hemorrhagic blisters), leave small to medium blisters intact when possible, but pierce and drain larger or troublesome blisters with a sterile needle while keeping the blister roof in place as a natural biological dressing. 1
Initial Assessment and Decision-Making
When to Leave Blisters Intact
- Small to medium blisters should generally be left intact to help prevent secondary bacterial infection 2, 3
- Asymptomatic blisters covering less than 10% body surface area require only observation or local wound care 4
When to Pierce and Drain
Pierce blisters when they are: 1, 3
- Particularly large in size
- Located in sites where they interfere with function (such as the sole of the foot) 2
- Causing significant discomfort or limiting activities
Proper Blister Drainage Technique
Follow this specific protocol for draining blisters: 1
Gently cleanse the blister with antimicrobial solution, taking care not to rupture it 1
Pierce the blister at its base with a sterile needle, with the bevel facing up 1
Gently apply pressure with sterile gauze swabs to facilitate drainage and absorb fluid 1
Do NOT deroof the blister - leave the blister roof in place as it acts as a biological dressing 1
Cleanse again with antimicrobial solution after fluid has drained 1
Apply a nonadherent dressing if necessary 1
Post-Drainage Care
Wound Protection and Healing
- Apply plain petrolatum ointment and bandages over any open erosions 4
- Alternatively, use plain petrolatum ointment gauze with bandage 4
- Apply bland emollient (such as 50% white soft paraffin and 50% liquid paraffin) to support barrier function, reduce water loss, and encourage re-epithelialization 1
Infection Prevention
- Use antiseptic baths or soaks (such as potassium permanganate) for a few days if there are extensive erosions to dry lesions and prevent infection 2
- Consider antiseptic-containing bath oils (e.g., Dermol Plus or Oilatum) 2
- Monitor vigilantly for signs of infection, as this increases risk of scarring 1
Pain Management
- Offer analgesia prior to blister care procedures, as many patients report pain or burning sensation during treatment 1
- Painful eroded areas may be covered with low-adhesion dressings such as Mepitel or Atrauman held in place with soft elasticated viscose 2
Important Caveats
Aspiration causes more discomfort than piercing - avoid aspirating blisters 1
If the blister is already broken, remove only the loose, fluttering skin rather than the entire roof 3
For friction or pressure blisters that are noninflammatory and asymptomatic, only observation or local wound care is needed 4