From the Guidelines
Enbrel (etanercept) is not typically known to cause foul-smelling urine as a direct side effect, but it may increase the susceptibility to urinary tract infections (UTIs) which can cause foul-smelling urine. The provided evidence does not directly address the relationship between Enbrel and foul-smelling urine [ 1 ]. However, it discusses the use of etanercept in the treatment of adult onset Still's disease, highlighting its efficacy and potential side effects, such as injection site reactions and infectious complications [ 1 ]. If you're experiencing foul-smelling urine while taking Enbrel, it is more likely due to a UTI rather than the medication itself. Key points to consider include:
- Enbrel works by suppressing parts of the immune system, which can increase susceptibility to infections, including UTIs.
- Symptoms of a UTI can include foul-smelling urine, burning during urination, increased frequency, urgency, or cloudy appearance.
- If you notice these symptoms, you should contact your healthcare provider promptly for proper evaluation and treatment.
- Your doctor may need to test your urine to check for infection and prescribe appropriate antibiotics if necessary.
- It's crucial not to discontinue Enbrel without medical advice, but your doctor might temporarily adjust your treatment if you have an active infection.
- Preventive measures such as staying well-hydrated and practicing good hygiene can help reduce the risk of UTIs while on immunosuppressive medications like Enbrel.
From the Research
Enbrel and Urine Odor
- There is no direct evidence in the provided studies that links Enbrel to foul urine odor.
- The studies focus on the use of Enbrel in treating various autoimmune diseases, such as rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, and its safety profile 2, 3, 4, 5.
- One study discusses urinary tract infections (UTIs) and their diagnosis, treatment, and prevention, but it does not mention Enbrel or its potential effects on urine odor 6.
- Therefore, based on the available evidence, there is no clear connection between Enbrel and foul urine odor.