From the Guidelines
Rhodiola rosea is not mentioned in the provided evidence, therefore, its effects cannot be determined based on the given studies 1.
Effects of Rhodiola Rosea
- No information is available in the provided evidence to determine the effects of Rhodiola rosea.
- The studies provided focus on the comparison of nonpharmacologic and pharmacologic treatments for major depressive disorder, including second-generation antidepressants, cognitive behavioral therapy, and complementary and alternative medicines such as St. John's wort and omega-3 fatty acids.
- Rhodiola rosea is not mentioned in any of the studies, and therefore, its potential anxiolytic and antidepressant effects cannot be evaluated based on the provided evidence. However, based on general knowledge, Rhodiola rosea has been studied for its potential anxiolytic and antidepressant effects, with typical dosages ranging from 100-200mg per day, and treatment durations varying but most studies investigating its efficacy over 6-12 weeks.
From the Research
Effects of Rhodiola rosea
The effects of Rhodiola rosea, also known as Golden Root or Arctic Root, have been studied in various research papers. Some of the key effects include:
- Adaptogenic properties, which help the body adapt to stress and increase resilience 2, 3
- Anti-fatigue and physical endurance enhancement properties 3
- Anxiolytic activity, which can help reduce anxiety disorders 4
- Antioxidant properties, which can help protect the body against oxidative stress 3
- Nootropic properties, which can help improve cognitive function 3
- Immunomodulatory properties, which can help regulate the immune system 3
Mechanisms of Action
The mechanisms of action of Rhodiola rosea are not fully understood, but some studies suggest that it may work by:
- Modulating the stress response system, including the hypothalamic-pituitary-adrenal (HPA) axis 3
- Increasing the production of neurotransmitters such as dopamine, serotonin, and norepinephrine 4
- Enhancing the activity of antioxidant enzymes, such as superoxide dismutase and glutathione peroxidase 3
- Interacting with GABA receptors, which can help regulate anxiety and stress responses 4
Clinical Trials
Some clinical trials have been conducted on Rhodiola rosea, including studies on its effects on anxiety disorders, fatigue, and cognitive function. These studies have shown promising results, but more research is needed to fully understand the effects of Rhodiola rosea on human health 4, 3