What type of dyslipidemia is characterized by hypercholesterolemia (elevated Total Cholesterol), hypertriglyceridemia (elevated Triglycerides), and hyperlow-density lipoprotein cholesterol (elevated LDL Chol Calc) with normal high-density lipoprotein (HDL) cholesterol levels?

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Differential Diagnosis for Dyslipidemia

The patient's lipid profile shows elevated total cholesterol, triglycerides, and LDL cholesterol, with normal HDL cholesterol. Based on these results, the following differential diagnoses can be considered:

  • Single Most Likely Diagnosis
    • Familial Combined Hyperlipidemia (FCHL): This condition is characterized by elevated levels of LDL cholesterol and triglycerides, which is consistent with the patient's lipid profile. FCHL is a common cause of dyslipidemia and is often associated with an increased risk of cardiovascular disease.
  • Other Likely Diagnoses
    • Familial Hypercholesterolemia (FH): Although the patient's LDL cholesterol level is elevated, it is not extremely high, which is often seen in FH. However, FH is still a possible diagnosis, especially if there is a family history of the condition.
    • Dysbetalipoproteinemia: This condition is characterized by elevated levels of VLDL cholesterol and triglycerides, which is consistent with the patient's lipid profile. However, the patient's VLDL cholesterol level is not extremely high, which makes this diagnosis less likely.
  • Do Not Miss Diagnoses
    • Nephrotic Syndrome: This condition can cause significant hyperlipidemia, including elevated levels of LDL cholesterol and triglycerides. Although it is not a common cause of dyslipidemia, it is a potentially life-threatening condition that should not be missed.
    • Hypothyroidism: Hypothyroidism can cause elevated levels of LDL cholesterol and triglycerides, and it is a common condition that can be easily diagnosed and treated.
  • Rare Diagnoses
    • Lipoprotein Lipase Deficiency: This is a rare genetic disorder that can cause significant hypertriglyceridemia. Although the patient's triglyceride level is elevated, it is not extremely high, which makes this diagnosis less likely.
    • Apolipoprotein C-II Deficiency: This is a rare genetic disorder that can cause significant hypertriglyceridemia. However, it is a rare condition that is often associated with other symptoms, such as pancreatitis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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