What is the diagnosis for a 63-year-old male with purulent discharge (pus) oozing from his toenail, suggestive of paronychia?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for 63-year-old Male with Pus Oozing from Toenail

  • Single most likely diagnosis:
    • Paronychia: This is an infection of the skin around the nail, which can cause pus to ooze from the toenail. It's a common condition, especially in older adults, and can be caused by bacterial or fungal infections.
  • Other Likely diagnoses:
    • Onychomycosis (fungal infection of the nail): This can lead to nail thickening, discoloration, and sometimes pus formation, especially if a bacterial infection is superimposed.
    • Ingrown toenail: This condition can cause redness, swelling, and sometimes pus, especially if the nail grows into the surrounding skin and causes an infection.
    • Cellulitis: A bacterial skin infection that can cause redness, swelling, and pus, especially if it involves the skin around the toenail.
  • Do Not Miss diagnoses:
    • Osteomyelitis (bone infection): Although less common, an infection of the bone underlying the toenail can cause pus to ooze from the nail and is a serious condition that requires prompt treatment.
    • Diabetic foot infection: In patients with diabetes, even a minor infection like paronychia can quickly become severe and lead to serious complications, including amputation.
    • Septic arthritis: If the infection spreads to the joint, it can cause septic arthritis, a serious condition that requires immediate medical attention.
  • Rare diagnoses:
    • Squamous cell carcinoma: A type of skin cancer that can cause ulceration and pus formation, although it's less common in the toenail area.
    • Melanonychia: A condition where melanin accumulates in the nail, causing discoloration, and can sometimes be mistaken for an infection.
    • Psoriatic nail dystrophy: A condition associated with psoriasis that can cause nail thickening, pitting, and sometimes pus formation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.