What is the total amount in grams of estradiol contained in a standard Estrace (estradiol) bottle?

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Estrace Bottle Contains 42.5 Grams

A standard Estrace vaginal cream bottle contains 42.5 grams (1½ oz) of cream. 1

Product Specifications

  • The bottle is supplied with a calibrated plastic applicator that can deliver 1,2,3, or 4 grams per application. 1
  • Each gram of the cream contains 0.1 mg of estradiol (0.01% concentration), meaning the full 42.5 g bottle contains approximately 4.25 mg of total estradiol. 1

Storage and Handling

  • Store at room temperature between 20°-25°C (59°-77°F) and protect from temperatures exceeding 40°C (104°F). 1
  • Keep out of reach of children. 1

Formulation Details

  • The cream is a smooth, semi-solid, white or off-white preparation in a nonliquefying base containing purified water, propylene glycol, stearyl alcohol, white ceresin wax, mono- and di-glycerides, hypromellose 2208, sodium lauryl sulfate, methylparaben, edetate disodium, and tertiary-butylhydroquinone. 1

References

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