From the Guidelines
For poison ivy topical treatment, I strongly recommend washing the affected area immediately with soap and lukewarm water to remove any remaining plant oil (urushiol), as this can remove up to 100% of the oil if done immediately after contact 1. This approach is crucial in reducing the severity of the allergic reaction.
- Washing with soap and water as soon as possible after exposure is the most effective way to prevent the spread of the rash and reduce its severity.
- Topical corticosteroids, such as hydrocortisone cream, may be used to reduce itching and inflammation, but their effectiveness is uncertain, especially for over-the-counter options 1.
- Cool compresses may be considered for relief of local symptoms, and oatmeal baths may also provide symptomatic relief, although the evidence for these treatments is limited 1.
- It is essential to avoid scratching the rash to prevent infection and seek medical attention if the rash covers large areas of the body, affects the face or genitals, shows signs of infection, or if fever or breathing difficulties develop. The use of systemic corticosteroids and high-potency topical corticosteroids may be necessary for more severe cases, as they have been shown to reduce the duration of itching 1.
- Oral antihistamines may be used to help with sleep at night, but their efficacy for itching is questionable, and their use should be based on individual patient needs and medical judgment 1.
From the FDA Drug Label
Uses temporarily relieves itching associated with minor skin irritations, inflammation, and rashes due to: eczema psoriasis poison ivy, oak, sumac insect bites detergents jewelry cosmetics soaps seborrheic dermatitis temporarily relieves external anal and genital itching
- Hydrocortisone (TOP) can be used as a topical treatment for poison ivy.
- It temporarily relieves itching associated with poison ivy. 2