What is the relationship between Cinnamomum burmannii and Chronic Kidney Disease (CKD)?

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From the Research

Cinnamomum burmannii (Indonesian cinnamon) should be used with caution in patients with chronic kidney disease (CKD) due to its high coumarin content, which may potentially worsen kidney function. The primary concern with using Cinnamomum burmannii in CKD patients is the potential for coumarin to cause hepatotoxicity and nephrotoxicity when consumed in large amounts over time 1. If a patient with kidney disease wishes to use cinnamon, Ceylon cinnamon (Cinnamomum verum) is a safer alternative as it contains much lower coumarin levels. For those with CKD who still want to use Indonesian cinnamon, consumption should be limited to no more than 1/4 teaspoon (0.5-1g) occasionally rather than daily. Additionally, patients with CKD should consult their nephrologist before using any cinnamon supplements, as cinnamon may interact with certain medications commonly prescribed for kidney disease, including some blood thinners and diabetes medications 2, 3. Some preliminary research suggests cinnamon may help with blood sugar control and inflammation, which could theoretically benefit CKD patients, but these potential benefits don't outweigh the risks of high-coumarin varieties for those with compromised kidney function 4, 5. Key considerations in managing CKD include reducing exposure to nephrotoxic substances, optimizing management of underlying conditions like hypertension and diabetes, and careful monitoring of kidney function and potential complications 2, 3, 5.

Key Points to Consider:

  • High coumarin content in Cinnamomum burmannii may worsen kidney function in CKD patients.
  • Ceylon cinnamon is a safer alternative due to its lower coumarin levels.
  • Limit consumption of Indonesian cinnamon to minimal amounts and only occasionally.
  • Consult a nephrologist before using cinnamon supplements, especially if on medications for kidney disease.
  • Managing CKD involves reducing nephrotoxic exposure, optimizing underlying condition management, and careful monitoring.

Recommendations for CKD Patients:

  • Use Ceylon cinnamon if possible.
  • Limit Indonesian cinnamon consumption.
  • Consult a nephrologist before using any cinnamon supplements.
  • Prioritize managing underlying conditions and reducing nephrotoxic exposure.

References

Research

Cinnamon: an aromatic condiment applicable to chronic kidney disease.

Kidney research and clinical practice, 2023

Research

Chronic kidney disease.

Lancet (London, England), 2021

Research

Kidney Disease: Chronic Kidney Disease.

FP essentials, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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