Dosing Calculation for Amoxicillin Suspension
For a 125 mg dose using amoxicillin suspension 125 mg/5 mL, you need to administer 5 mL.
Direct Answer from FDA Labeling
The calculation is straightforward based on the concentration:
- Amoxicillin suspension 125 mg/5 mL means that each 5 mL contains exactly 125 mg of amoxicillin 1
- To deliver a 125 mg dose, administer 5 mL of the suspension 1
Practical Administration Details
Preparation and measurement:
- The reconstituted suspension provides a final concentration of 6 mg/mL when properly mixed 1
- For the 125 mg/5 mL formulation, a 30 mg dose requires 5 mL, a 45 mg dose requires 7.5 mL, a 60 mg dose requires 10 mL, and a 75 mg dose requires 12.5 mL 1
- The suspension should be shaken well before each use 1
Storage considerations:
- After reconstitution, the suspension must be discarded after 14 days 1
- Refrigeration is preferable but not required 1
- The suspension should be kept in a tightly closed bottle 1
Common Pitfall to Avoid
Do not confuse the 125 mg/5 mL concentration with the 250 mg/5 mL concentration, as both are available formulations 1. Always verify which concentration you have dispensed before calculating the volume to administer.