Is daily tadalafil (Cialis) used for increasing longevity?

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Last updated: April 29, 2025View editorial policy

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From the Guidelines

Daily Cialis (tadalafil) is not approved or proven for longevity purposes. Cialis is a medication specifically designed to treat erectile dysfunction and benign prostatic hyperplasia (enlarged prostate). The standard daily dose for erectile dysfunction is typically 2.5 to 5 mg taken once daily, regardless of sexual activity timing. While Cialis improves blood flow by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which relaxes blood vessels, there is no scientific evidence supporting its use for extending lifespan or promoting general longevity, as noted in a study on testosterone treatment in adult men with age-related low testosterone 1. Some people may confuse the cardiovascular benefits of improved blood flow with longevity effects, but these are distinct concepts.

Using Cialis without a medical need can lead to side effects including headaches, indigestion, back pain, muscle aches, flushing, and nasal congestion. Additionally, it can interact dangerously with nitrate medications and cause severe drops in blood pressure. Any medication use should be discussed with and prescribed by a healthcare provider based on specific medical needs rather than unproven longevity claims. It's also important to consider that the evidence on mortality and longevity is often based on studies with specific populations and conditions, such as those with pulmonary hypertension 1, and may not be applicable to the general population or those without specific medical conditions.

Key points to consider:

  • Cialis is not approved for longevity purposes
  • It is designed to treat erectile dysfunction and benign prostatic hyperplasia
  • Improved blood flow does not directly translate to longevity effects
  • Potential side effects and interactions should be considered
  • Medication use should be based on medical need and prescribed by a healthcare provider, as supported by studies such as those on testosterone treatment 1 and pediatric pulmonary hypertension 1.

From the Research

Daily Cialis for Longevity

  • The concept of daily Cialis, also known as tadalafil, being used for longevity is not directly addressed in the provided studies 2, 3, 4, 5, 6.
  • However, the studies do explore the efficacy and safety of tadalafil in the treatment of erectile dysfunction (ED), which can be related to overall health and well-being.
  • Tadalafil has been shown to be effective in improving ED symptoms in patients with various conditions, including diabetes and blood circulation issues 3.
  • The long-term safety and tolerability of tadalafil have also been established, with studies showing that it can be safely used for up to 24 months 4.
  • Daily tadalafil use has been compared to on-demand use, with some studies suggesting that daily use may be more effective in improving ED symptoms 5.
  • Tadalafil has also been shown to be effective in men with severe ED, with significant improvements in intercourse success rates and overall satisfaction 6.

Key Findings

  • Tadalafil is effective in improving ED symptoms in patients with various conditions, including diabetes and blood circulation issues 3.
  • Long-term use of tadalafil is safe and well-tolerated, with no significant changes in cardiac indicators or laboratory tests 4.
  • Daily tadalafil use may be more effective than on-demand use in improving ED symptoms 5.
  • Tadalafil is effective in men with severe ED, with significant improvements in intercourse success rates and overall satisfaction 6.

Study Limitations

  • The studies provided do not directly address the concept of daily Cialis being used for longevity.
  • The studies primarily focus on the efficacy and safety of tadalafil in the treatment of ED, rather than its potential effects on longevity.
  • Further research is needed to fully understand the potential benefits and risks of daily tadalafil use for longevity 2, 3, 4, 5, 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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