From the FDA Drug Label
Amoxicillin and clavulanate potassium tablets, USP is an oral antibacterial combination consisting of amoxicillin and the β-lactamase inhibitor, clavulanate potassium (the potassium salt of clavulanic acid). Chemically, amoxicillin, USP is ( 2S, 5R, 6R)-6-[( R)-(-)-2-Amino-2-( p-hydroxyphenyl)acetamido]-3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a beta-lactam structurally related to the penicillins and possesses the ability to inactivate some beta-lactamases by blocking the active sites of these enzymes. Inactive Ingredients: colloidal silicon dioxide, ethylcellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, talc and titanium dioxide.
Key Ingredients:
- Amoxicillin
- Clavulanic acid (beta-lactam)
- Inactive ingredients (listed above)
Sulfonamide (Sulfa) Content: There is no mention of sulfonamide or sulfa in the provided drug labels 1 and 1.
The FDA drug label does not answer the question.
From the Research
Augmentin Composition
- Augmentin, also known as amoxicillin-clavulanate, is a broad-spectrum antibacterial agent that consists of amoxicillin and clavulanic acid 2, 3, 4, 5, 6.
- The combination of amoxicillin and clavulanic acid provides a potent broad-spectrum of antibacterial activity, coverage of beta-lactamase-producing pathogens, and a favorable pharmacokinetic/pharmacodynamic profile 2.
Sulfonamide (Sulfa) Content
- There is no mention of sulfonamide (sulfa) in the composition of Augmentin in the provided studies 2, 3, 4, 5, 6.
- The studies focus on the efficacy and tolerance of amoxicillin-clavulanate in various infections, but do not discuss the presence of sulfonamide (sulfa) in the medication.