Can Valium (diazepam) be used to treat headaches?

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Last updated: April 30, 2025View editorial policy

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From the Guidelines

Valium is not recommended for treating headaches, as it is not an effective treatment for this condition and can lead to dependence and addiction. According to the American College of Physicians guideline on pharmacologic treatments of acute episodic migraine headache in outpatient settings 1, the recommended treatments for mild episodic migraine headache include NSAIDs, acetaminophen, or the combination of an NSAID and acetaminophen. For moderate to severe acute episodic migraine headache, options such as CGRP antagonists-gepants, ergot alkaloid, or the ditan lasmiditan may be considered.

  • Key points to consider when treating headaches include:
    • Using combination therapy, such as a triptan with an NSAID or acetaminophen, to improve efficacy
    • Counseling patients to begin treatment as soon as possible after headache onset
    • Discussing the potential risks of medication overuse headache, which can occur with frequent use of headache medications
    • Considering preventive medications if episodic migraine occurs frequently or treatment does not provide an adequate response
  • It is essential to consult with a healthcare provider to determine the best course of treatment for headaches, as they can recommend appropriate treatment based on the specific headache type and medical history, as suggested by the guideline 1.

From the Research

Treatment Options for Headache

  • The studies 2, 3, 4, 5 suggest that various medications can be used to treat headaches, including acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), triptans, and combination products that include caffeine.
  • For mild to moderate migraine attacks, oral NSAIDs are recommended as the first choice, with oral aspirin, combination analgesics, intravenous/intramuscular NSAIDs as alternatives 3.
  • For moderate to severe attacks, oral or nasal spray triptans and ergotamine/caffeine compounds are recommended and should be administered in the early stage of migraine attacks 3.

Use of Valium for Headache

  • There is no direct evidence in the provided studies to support the use of Valium (diazepam) as a treatment for headache.
  • The studies focus on the use of other medications such as NSAIDs, triptans, and combination products for the treatment of migraine and other headache disorders.
  • It is not recommended to use Valium or other benzodiazepines as a first-line treatment for headache without consulting a healthcare professional, as they may have adverse effects and interact with other medications.

Alternative Treatment Options

  • The studies 2, 3, 4, 5 suggest that other treatment options such as gepants, lasmiditan, and preventive treatments like antihypertensives, antiepileptics, and calcitonin gene-related peptide monoclonal antibodies may be effective for the treatment of migraine and other headache disorders.
  • It is essential to consult a healthcare professional to determine the best course of treatment for individual cases of headache, as the effectiveness and safety of different medications can vary depending on the specific condition and patient characteristics.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Acute Migraine Headache: Treatment Strategies.

American family physician, 2018

Research

Medical Treatment Guidelines for Acute Migraine Attacks.

Acta neurologica Taiwanica, 2017

Research

Symptomatic treatment of migraine: when to use NSAIDs, triptans, or opiates.

Current treatment options in neurology, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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