From the Research
Effects of Serenol on Mood
There is no direct evidence of the effects of Serenol on mood in the provided studies. However, the studies do discuss the effects of Vitex agnus castus, which is an ingredient in Serenol, on premenstrual syndrome (PMS) symptoms, including mood-related symptoms.
Studies on Vitex Agnus Castus
- A systematic review and meta-analysis of 17 randomized controlled trials found that Vitex agnus castus preparations had a positive effect on total PMS symptoms, including mood-related symptoms, in 13 out of 14 studies 1.
- A real-world, interventional, comparative study found that a nutraceutical composition containing Vitex agnus-castus extract, pyridoxine, and magnesium improved PMS symptoms, including mood-related symptoms, in women with PMS 2.
- A multicenter, double-blind, placebo-controlled, parallel-group study found that Vitex agnus castus extract Ze 440 was effective in relieving symptoms of PMS, including mood-related symptoms, at a dose of 20mg per day 3.
- A systematic review of eight randomized controlled trials found that Vitex agnus castus was a safe and effective treatment for PMS and premenstrual dysphoric disorder (PMDD), including symptoms related to mood 4.
- A prospective, open-label study found that Vitex agnus-castus extract improved PMS symptoms, including mood-related symptoms, in Japanese patients with PMS 5.
Key Findings
- Vitex agnus castus preparations have been found to have a positive effect on PMS symptoms, including mood-related symptoms.
- The optimal dose of Vitex agnus castus extract for relieving PMS symptoms is 20mg per day.
- Vitex agnus castus is generally well-tolerated and safe for use in women with PMS.