What is 2CP (2-Cyclopropylphenol)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Article Review Status
Submitted
Under Review
Approved

Last updated: April 30, 2025 • View editorial policy

From the Research

2CP, or 2,5-Dimethoxy-4(n)-propylphenethylamine, is a synthetic psychedelic drug that belongs to the phenethylamine class of compounds, known for its hallucinogenic properties and potential risks including psychological distress, cognitive impairment, and addiction. The chemical structure of 2CP is distinct, with a propyl group in the 4 position of the phenyl ring, which differentiates it from other compounds like 2C-B, which has a bromine in that position 1. Some key points about 2CP include:

  • It produces hallucinogenic and dissociative effects when consumed, with a duration of action that can vary but has been estimated to have an elimination half-life of 19 hours in one case report 1.
  • The typical dosage range and effects can vary based on individual sensitivity, but users report visual distortions, altered perception of time, and dissociative effects.
  • 2CP is not approved for medical use and is considered a research chemical with an unknown safety profile, carrying significant risks including psychological distress, cognitive impairment, and potential for addiction.
  • The mechanism of action likely involves receptor affinity and potency similar to other drugs in its class, but specific details on its pharmacodynamics and pharmacokinetics, such as NMDA receptor antagonism and serotonergic activity, are not well-documented in the provided evidence.
  • It's crucial to note that possession or distribution of 2CP may be illegal in many jurisdictions under analog drug laws, even if not specifically scheduled, highlighting the need for caution and awareness of legal implications. Given the potential for severe psychological and physical effects, and considering the most recent and highest quality study available 1, it is essential to approach 2CP with caution, recognizing its potential for harm and the lack of comprehensive medical and legal oversight.

References

Research

Mistaking 2C-P for 2C-B: What a Difference a Letter Makes.

Journal of analytical toxicology, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.