What is the recommended A1c (glycated hemoglobin) target for patients using Omnipod 5 (insulin pump system) in auto mode?

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From the Research

For patients using the Omnipod 5 in Auto Mode, the recommended Active Insulin Time (AIT) setting is 5 hours. This setting is specifically designed to work with the Omnipod 5's algorithm to optimize automated insulin delivery, as seen in the study published in Diabetes Care 1. The 5-hour AIT accounts for the full physiological action of insulin in the body, extending beyond the peak effect time, and is used by the system to track insulin on board (IOB) and make adjustments to basal insulin delivery based on continuous glucose monitoring data. Key points to consider include:

  • The Omnipod 5 system's automated algorithm relies on this fixed 5-hour AIT setting to calculate insulin dosing decisions.
  • Patients and providers should be aware that this setting is intentional and should not attempt to modify it when switching from other insulin pumps that may have used shorter AIT settings.
  • The study published in Diabetes Care 1 demonstrates the safety and efficacy of the Omnipod 5 Automated Insulin Delivery System in adults with type 2 diabetes, supporting the use of this AIT setting in clinical practice. Other studies, such as those published in Kidney International 2, Journal of Clinical Medicine Research 3, Current Diabetes Reports 4, and Medicine 5, provide additional context on the management of diabetes and cardiovascular risk, but do not directly impact the recommended AIT setting for the Omnipod 5 in Auto Mode.

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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