What is the diagnosis for a 30-year-old female with bilateral otalgia (ear pain), pharyngitis (sore throat), postnasal drip, and cough for 11 days, with a negative streptococcal test, who has been taking Flonase (fluticasone) for a week and now experiences worsening symptoms with shortness of breath (dyspnea)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 30, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for 30-year-old Female with Respiratory Symptoms

  • Single most likely diagnosis:
    • Acute sinusitis: The patient's symptoms of bilateral ear pain, sore throat, postnasal drip, and cough, along with the use of Flonase (a nasal steroid) for a week, suggest a diagnosis of acute sinusitis. The worsening of symptoms despite treatment could indicate a bacterial superinfection or inadequate treatment of the underlying cause.
  • Other Likely diagnoses:
    • Acute bronchitis: The patient's cough and shortness of breath (SOB) could be indicative of acute bronchitis, especially if the sinusitis has led to a postnasal drip that is irritating the bronchial tubes.
    • Allergic rhinitis: Although the patient is already on Flonase, the symptoms of postnasal drip and sore throat could also be consistent with allergic rhinitis, especially if the allergies are not well-controlled.
    • Viral pharyngitis: Given the negative strep test, viral pharyngitis is a possible cause of the sore throat, and the other symptoms could be related to a viral upper respiratory infection.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Epiglottitis: Although rare, epiglottitis is a life-threatening condition that can cause severe sore throat, difficulty swallowing, and shortness of breath. It requires prompt recognition and treatment.
    • Pneumonia: The patient's cough and shortness of breath could also be indicative of pneumonia, especially if the symptoms are severe or worsening despite treatment.
    • Angioedema: If the patient has a history of allergies, angioedema could be a consideration, especially if the symptoms include swelling of the face, lips, or tongue.
  • Rare diagnoses:
    • Vasculitis (e.g., Wegener's granulomatosis): This is a rare autoimmune disorder that can cause a variety of symptoms, including sinusitis, sore throat, and cough.
    • Sarcoidosis: This is a rare inflammatory disease that can affect multiple organs, including the lungs and sinuses, and cause a variety of symptoms.
    • Relapsing polychondritis: This is a rare autoimmune disorder that can cause inflammation of the cartilage in the ears, nose, and trachea, leading to symptoms such as ear pain and shortness of breath.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.