From the Guidelines
The dosage and duration of Emma pen (penicillin) for bacterial infections is 12-18 million U per 24 h IV for 4 weeks, as recommended for native valve endocarditis caused by highly penicillin-susceptible viridans group streptococci and Streptococcus bovis 1.
Key Considerations
- The dosage can be administered continuously or in 4 or 6 equally divided doses 1.
- For patients with normal renal function, the recommended dosage is 12-18 million U per 24 h IV 1.
- The duration of treatment can be 2 weeks for certain patients, but this regimen is not intended for patients with known cardiac or extracardiac abscess or for those with creatinine clearance of less than 20 ml per min, impaired 8th cranial nerve function, or Abiotrophia, Granulicatella, or Gemella spp infection 1.
Alternative Regimens
- Ceftriaxone sodium can be used as an alternative, with a dosage of 2 g per 24 h IV/IM in 1 dose for 4 weeks 1.
- Vancomycin hydrochloride can be used for patients unable to tolerate penicillin or ceftriaxone, with a dosage of 30 mg per kg per 24 h IV in 2 equally divided doses not to exceed 2 g per 24 h unless concentrations in serum are inappropriately low 1.
From the Research
Dosage and Duration of Emma Pen (Penicillin) for Bacterial Infections
There are no research papers to assist in answering this question, as the provided studies focus on the treatment of status epilepticus and do not mention the use of penicillin or Emma pen for bacterial infections.
- The studies 2, 3, 4, 5, 6 discuss the treatment of status epilepticus, including the use of benzodiazepines, phenytoin, and other anti-epileptic drugs, but do not provide information on the dosage and duration of penicillin for bacterial infections.
- The provided evidence does not support the use of Emma pen (penicillin) for the treatment of status epilepticus, and therefore, does not provide guidance on the dosage and duration of treatment for bacterial infections.