What is the Blalock-Taussig Shunt?
The Blalock-Taussig (BT) shunt is a palliative surgical procedure that creates a connection between the systemic arterial circulation and the pulmonary arteries to increase pulmonary blood flow in patients with cyanotic congenital heart disease, most commonly performed as a modified version using an interposition graft. 1
Historical Context and Evolution
The BT shunt was first described in 1945 and represented the first direct surgical procedure for treating cyanotic congenital heart disease. 2 Over more than six decades of use, the procedure has undergone significant modifications while remaining an integral component of managing cyanotic heart defects. 3
Types of Blalock-Taussig Shunts
Classic BT Shunt
- Direct end-to-side anastomosis of the subclavian artery to the pulmonary artery 4
- Historically more common but now largely replaced by the modified technique 5
Modified BT Shunt
- Uses an interposition graft (typically expanded polytetrafluoroethylene) to connect the subclavian artery to the pulmonary artery 4, 1
- Currently represents 99.6% of all BT shunts performed 3
- The modified BT shunt is technically simpler with less dissection, preserves blood flow to the arm, and has demonstrated superior outcomes regarding hemodynamics, patency rate, and survival compared to the classic approach 1
Primary Indications
The BT shunt serves as a palliative procedure to augment pulmonary blood flow in several clinical scenarios:
- Tetralogy of Fallot (TOF): The most common indication, particularly in symptomatic neonates where early complete repair is not feasible 6, 5
- Single ventricle lesions: Increasingly used as part of staged palliation toward eventual Fontan completion 3, 5
- Pulmonary atresia with ventricular septal defect 6
- Complex cyanotic congenital heart defects with inadequate pulmonary blood flow 1, 3
Surgical Technique and Approach
Anatomic Considerations
- Predominantly performed on the right side (90% of cases) 3
- Most common configuration: right subclavian artery to right pulmonary artery 3
- Can be performed via sternotomy (65% of cases) or thoracotomy (35% of cases) 3, 7
Approach-Related Outcomes
Thoracotomy approach demonstrates lower morbidity compared to sternotomy, with significantly shorter ventilation duration (53 hours vs 183 hours), reduced inotropic requirements (4.2% vs 33.3%), shorter ICU stay (3.3 days vs 9.14 days), and shorter hospital stay (5 days vs 14.59 days). 7
Contemporary Outcomes
Mortality
- Modern operative mortality ranges from 1-9% in specialized centers 4, 3, 2
- Hospital mortality is significantly higher in single ventricle patients compared to biventricular lesions (15% vs 3%) 3
- Mortality is primarily related to patient condition at surgery and underlying cardiac pathology rather than age 2
Risk Factors for Mortality
Multivariable analysis identifies the following as independent risk factors for in-hospital mortality:
- Sternotomy approach 3
- Use of cardiopulmonary bypass 3
- Innominate artery-to-pulmonary artery shunt configuration 3
- Specific diagnoses such as Ebstein's anomaly 3
Role in Modern Management
For Tetralogy of Fallot
When palliation is chosen for symptomatic neonates with TOF, systemic-to-pulmonary shunt (most commonly modified BT shunt) is a reasonable strategy alongside alternatives including RVOT patch and right ventricle-to-pulmonary artery conduit (Class IIa recommendation). 6
The decision between palliation and primary repair depends on:
- Patient age and weight 6
- Severity of symptoms 6
- Anatomy of pulmonary arteries 6
- Institutional expertise 6
Advantages of BT Shunt
- Excellent pulmonary artery growth observed in patients with modified BT shunt 1
- Can be performed on patients of any age with minimum postoperative complications 1
- Expanded polytetrafluoroethylene grafts have demonstrated satisfactory long-term patency 1
- 73% of patients are successfully bridged to complete repair or second stage palliation after median duration of 6.5 months 3
Evolving Landscape
- Decreasing overall use of BT shunts over time (from 66 per year to 9 per year comparing early vs late eras) 5
- Shift toward transcatheter interventions (ductal stenting) in selected high-risk patients at centers with demonstrated expertise 6
- Greater application to single-ventricle lesions in contemporary practice (34% vs 5% comparing recent vs historical eras) 5