What is the role of Artificial Intelligence (AI) in Electrocardiograms (EKGs)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 1, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Artificial intelligence (AI) should be adopted as a supportive tool in EKG analysis to enhance diagnostic accuracy and patient outcomes, as evidenced by a recent study published in Circulation in 2024 1. The use of AI in EKG interpretation has shown promising results in detecting occult structural heart disease, including left ventricular dysfunction, hypertrophic cardiomyopathy, and atrial fibrillation, with an area under the curve (AUC) of 0.92 for ventricular dysfunction detection 1. Key benefits of AI in EKG analysis include:

  • Early detection of structural heart disease, up to 1 to 2 years earlier than traditional testing 1
  • Improved diagnostic accuracy, with an AUC of 0.87 for identifying silent atrial fibrillation 1
  • Enhanced patient outcomes, with a 32% improvement in first detection of ventricular dysfunction over usual care 1 To effectively implement AI in EKG analysis, healthcare facilities should:
  • Invest in FDA-approved AI platforms that integrate with existing EKG machines and electronic health records
  • Provide staff training on understanding AI capabilities and limitations
  • Ensure human oversight to address rare conditions or unusual presentations, as AI may struggle with these cases 1.

From the Research

AI for EKGs

  • Artificial intelligence (AI) is transforming electrocardiography (ECG) interpretation, enabling automated access to nuanced ECG interpretation and expanding the scope of cardiovascular screening in the population 2.
  • AI-ECG models have been developed for various applications, including:
    • Rhythm classification
    • Screening for structural heart disease, such as hypertrophic cardiomyopathy, cardiac amyloidosis, and left ventricular systolic dysfunction
    • Predicting future events, like development of systolic heart failure and atrial fibrillation
    • Acute cardiac events and non-cardiac applications, including acute pulmonary embolism and sleep apnea 2, 3
  • AI-enabled ECG algorithms have demonstrated high diagnostic performance, comparable to practicing cardiologists, in interpreting standard 12-lead ECGs 4, 5.
  • The use of AI in ECG analysis has several benefits, including quick and precise detection of problems, enhanced interpretation, diagnosis, risk assessment, and disease management 5, 6.
  • However, there are limitations and challenges to the effective implementation of AI-powered ECG analysis, such as systematic bias, inadequate generalization, regulatory barriers, and interpretability concerns 5, 3.
  • To address these issues, diverse dataset curation, bias mitigation strategies, continuous validation across populations, and collaborative efforts for regulatory approval are essential for the successful deployment of AI ECG in clinical settings 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.