Rosuvastatin 10mg Brand Availability
Rosuvastatin 10mg is widely available as a generic medication from multiple manufacturers, with Crestor® being the original brand name product from AstraZeneca. 1
Brand and Generic Information
Crestor® is the original brand-name rosuvastatin licensed to AstraZeneca from Shionogi, and was the first formulation approved for clinical use 2
Generic rosuvastatin is now extensively available and widely used, with multiple manufacturers producing FDA-approved generic versions 1
The generic formulation has demonstrated comparable efficacy, safety, and clinical outcomes to brand-name statins, with the added benefit of approximately 16% reduction in medical expenses per patient 3
Physical Description of 10mg Tablets
The FDA-approved rosuvastatin 10mg tablets are described as: pink colored, round, biconvex, film-coated tablets 1
- Generic versions may have different markings depending on the manufacturer (e.g., "SG on one side and 117 on other side" for one generic formulation) 1
Clinical Context for 10mg Dosing
Rosuvastatin 10mg is classified as moderate-intensity statin therapy, producing approximately 30-49% LDL-C reduction 4
This dose is appropriate for many patients requiring moderate-intensity therapy, including those with established atherosclerotic cardiovascular disease who cannot tolerate high-intensity therapy 4
The 10mg dose is the maximum recommended dose for patients taking certain concomitant medications (cyclosporine requires ≤5mg; teriflunomide, enasidenib, capmatinib, and regorafenib require ≤10mg) 1
Practical Considerations
Generic rosuvastatin is the most cost-effective option and should be preferentially used in most clinical scenarios 3
For Asian patients, 5mg is the recommended starting dose due to increased plasma concentrations, with careful consideration needed before escalating beyond 20mg 1
In patients with severe renal impairment (CrCl <30 mL/min/1.73 m²) not on hemodialysis, the starting dose is 5mg and should not exceed 10mg daily 1