What are the UK guidelines for inframammary fold (breast fold) infections?

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Last updated: May 1, 2025View editorial policy

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From the Research

For breast fold infections in the UK, the recommended approach is to first clean the area with mild soap and water, keeping it dry afterward, and consider using moisture-wicking textiles within skin folds to reduce skin-on-skin friction and wick away moisture, as suggested by the most recent study 1.

Key Recommendations

  • For mild infections, topical antibiotics like fusidic acid cream applied 3-4 times daily for 7-10 days are typically prescribed.
  • For more severe infections, oral antibiotics such as flucloxacillin 500mg four times daily for 7-14 days are recommended, with clarithromycin 500mg twice daily as an alternative for those with penicillin allergies.
  • Patients should also wear supportive, non-underwired bras, avoid skin-to-skin contact by using cotton or absorbent materials between skin folds, and maintain good hygiene.

Importance of Hygiene and Skin Care

The importance of keeping the area clean and dry cannot be overstated, as moisture trapped in the breast fold can create an environment for bacterial growth, particularly Staphylococcus aureus and Streptococcus species, as noted in various studies 2, 3.

Monitoring and Follow-up

If symptoms worsen or don't improve within 48 hours of treatment, patients should seek medical attention, highlighting the need for close monitoring and follow-up in the management of breast fold infections.

Limitations and Future Directions

Despite the availability of some guidance, there remains a lack of clear, evidence-based guidelines for the management of breast infections, including breast fold infections, as highlighted by studies 2, 4, 5, underscoring the need for further research and the development of standardized protocols to improve patient outcomes.

References

Research

Breast infections: A review of current literature.

American journal of surgery, 2024

Research

Breast Infection: A Review of Diagnosis and Management Practices.

European journal of breast health, 2018

Research

Management of periprosthetic breast infection: a systematic review and meta-analysis.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2021

Research

Variation in the management of ductal carcinoma in situ in the UK: Results of the Mammary Fold National Practice Survey.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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