Are small pericardial effusions a normal finding in pregnancy?

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Last updated: May 1, 2025View editorial policy

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From the Guidelines

Small pericardial effusions are not entirely normal in pregnancy, and their presence warrants clinical evaluation to determine the underlying cause and appropriate management. The development of pericardial effusion during pregnancy can be due to various factors, including pregnancy-induced hypertension, cardiac or systemic disorders, or other conditions such as hypothyroidism 1. While some studies suggest that a minimal to moderate clinically silent hydropericardium may develop in many pregnant women by the third trimester, this finding should not be dismissed as a normal physiological change of pregnancy 1. Key considerations in the management of pericardial effusion during pregnancy include:

  • Determining the size of the effusion and evaluating for signs of cardiac tamponade using echocardiography
  • Assessing the underlying cause, severity of symptoms, and hemodynamic impact
  • Monitoring asymptomatic small effusions with serial echocardiograms
  • Considering more aggressive intervention for larger or symptomatic effusions
  • Consulting with both obstetric and cardiac specialists to ensure optimal maternal and fetal outcomes It is essential to note that the presence of a pericardial effusion during pregnancy may require careful management, including the use of medications such as aspirin or prednisone, and avoiding certain medications like colchicine due to potential risks to the fetus 1. Overall, a thorough clinical evaluation and individualized management approach are necessary to ensure the best possible outcomes for pregnant women with pericardial effusions.

From the Research

Pericardial Effusions in Pregnancy

  • Small pericardial effusions are commonly found in pregnant women, with approximately 40% of healthy pregnant women having a small, clinically silent pericardial effusion in the third trimester 2.
  • These effusions are typically benign, mild, or moderate, and are well tolerated, with spontaneous resolution after delivery 3.
  • The presence of a small pericardial effusion in pregnancy is not necessarily a cause for concern, but larger effusions can be a sign of an underlying condition such as hydrops fetalis, Rh disease, hypoalbuminemia, or an infectious or autoimmune disorder 2.

Diagnosis and Management

  • Echocardiography is a key tool in the diagnosis and management of pericardial effusions in pregnancy, allowing for the assessment of the quantity and quality of pericardial fluid, as well as the hemodynamic impact of the effusion 4, 5.
  • In cases of cardiac tamponade, immediate intervention is necessary, and echocardiography can provide instant confirmation of the diagnosis and guide treatment decisions 5, 6.
  • Treatment of pericardial effusions in pregnancy typically involves monitoring and supportive care, with pericardiocentesis or other interventions only necessary in cases of large or hemodynamically significant effusions 3, 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Pericardial Diseases in Pregnancy.

The Canadian journal of cardiology, 2023

Research

[Pericardial effusion. Differential diagnostics, surveillance and treatment].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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