Is chronic use of Prilosec (Omeprazole) associated with the development of Gastrointestinal Stromal Tumors (GIST)?

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From the Research

Association between Prilosec (Omeprazole) and Gastrointestinal Stromal Tumors (GIST)

  • There is no direct evidence in the provided studies to suggest a link between the chronic use of Prilosec (Omeprazole) and the development of Gastrointestinal Stromal Tumors (GIST) 1, 2, 3, 4, 5.
  • The studies primarily focus on the pharmacology, pharmacokinetics, and effects of omeprazole on gastric acid secretion and its use in treating conditions like duodenal ulcers and reflux oesophagitis.
  • None of the studies mention GIST or investigate the long-term effects of omeprazole on the development of such tumors.
  • Therefore, based on the provided evidence, there are no research papers to assist in answering this question regarding the association between chronic omeprazole use and GIST development.

References

1
Research

Effect of omeprazole on gastric acid secretion and plasma gastrin in man.

Scandinavian journal of gastroenterology. Supplement, 1989

3
Research

Effect of omeprazole on gastric acid secretion and plasma gastrin.

Journal of gastroenterology and hepatology, 1989

4
Research

Prophylaxis and treatment of non-steroidal anti-inflammatory drug-induced upper gastrointestinal side-effects.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2001

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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