What are the differential diagnoses for hand pain (arthralgia)?

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Differential Diagnosis for Pain in Hands

Single Most Likely Diagnosis

  • Osteoarthritis: This is a common condition characterized by wear and tear of the joints, leading to pain and stiffness, especially in the hands. It's more prevalent in older adults and those with a family history of the condition.

Other Likely Diagnoses

  • Rheumatoid Arthritis: An autoimmune disorder that causes inflammation and pain in the hands and other joints. It often presents with symmetrical joint involvement and morning stiffness.
  • Carpal Tunnel Syndrome: A condition that arises from compression of the median nerve in the wrist, leading to pain, numbness, and tingling in the hand, particularly at night.
  • Tendinitis: Inflammation of the tendons, which can cause pain and stiffness in the hands, often related to overuse or repetitive strain injuries.
  • Gout: A form of arthritis characterized by sudden, severe attacks of pain, swelling, redness, and tenderness in one or more joints, sometimes affecting the hands.

Do Not Miss Diagnoses

  • Septic Arthritis: A bacterial infection within a joint, which is a medical emergency requiring prompt antibiotic treatment to prevent joint destruction and systemic complications.
  • Ganglion Cyst: A lump under the skin that occurs near joints or tendons, which can cause pain if it presses on a nerve.
  • Raynaud's Phenomenon: A condition that affects blood flow to the fingers and toes, and sometimes the ears, nose, and lips, triggered by cold or stress, leading to discoloration and pain.

Rare Diagnoses

  • Scleroderma: A chronic autoimmune disease characterized by thickening of the skin and connective tissue, which can lead to hand pain, stiffness, and limited mobility.
  • Ehlers-Danlos Syndrome: A group of disorders that affect connective tissues supporting the skin, bones, blood vessels, and many other organs and tissues, sometimes causing joint hypermobility and pain.
  • Psoriatic Arthritis: A type of arthritis that occurs in some people with psoriasis, leading to joint pain, stiffness, and swelling, including in the hands.
  • Sarcoidosis: A disease in which granulomas (abnormal masses of inflamed tissue) form in certain parts of the body, including the hands, causing pain and swelling.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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