Can erythema infectiosum (fifth disease) cause abdominal pain?

From the Research

Fifth disease can cause abdominal pain, although it is not a common symptom, and the pain is usually mild and self-limiting. The primary symptoms of fifth disease typically include a distinctive "slapped cheek" rash, mild fever, headache, and joint pain. Abdominal pain occurs in some cases, particularly in children, and is usually managed with over-the-counter pain relievers like acetaminophen (Tylenol) at appropriate age-based dosing 1.

Key Considerations

• The virus works by infecting rapidly dividing cells, including those in the intestinal tract, which can lead to inflammation and discomfort in the abdominal region.
• If abdominal pain occurs with fifth disease, it is essential to stay hydrated and rest while the infection runs its course.
• Most cases of fifth disease resolve on their own within 1-3 weeks without specific treatment.
• If abdominal pain is severe, persistent, or accompanied by other concerning symptoms like severe vomiting or bloody stools, medical attention should be sought as these are not typical of uncomplicated fifth disease and may indicate another condition 2, 3.

Management and Treatment

• Over-the-counter pain relievers like acetaminophen (Tylenol) can be used to manage abdominal pain at appropriate age-based dosing.
• Staying hydrated and resting while the infection runs its course is crucial.
• Medical attention should be sought if abdominal pain is severe, persistent, or accompanied by other concerning symptoms.

Diagnosis and Evaluation

• The diagnosis of fifth disease is typically based on clinical presentation, including the distinctive "slapped cheek" rash and other symptoms.
• If abdominal pain is present, a thorough evaluation should be conducted to rule out other causes of abdominal pain, including inflammatory bowel disease, gastroenteritis, and other conditions 4, 1.