What is the duration of Mirena (levonorgestrel) intrauterine device (IUD) effectiveness?

From the Guidelines

Mirena, a levonorgestrel-releasing intrauterine device, is approved for 5 years, but data suggest it remains effective for up to 7 years. The device is a highly effective form of contraception, with a failure rate of less than 1% 1. It works by releasing a small amount of levonorgestrel directly into the uterus, thickening cervical mucus, inhibiting sperm movement, reducing sperm survival, and thinning the uterine lining.

Key Points

• Mirena is approved for 5 years, but its effectiveness may extend up to 7 years 1
• It is a highly effective form of contraception, with a failure rate of less than 1% 1
• The device can cause irregular bleeding or spotting in the first 3-6 months, which typically improves over time 1
• Many users experience lighter periods or no periods at all while using Mirena 1

Considerations

• Mirena can be removed at any time by a healthcare provider if pregnancy is desired, with fertility typically returning quickly after removal
• The device is suitable for adolescents and is generally safe and effective, with no increased risk of pelvic infection or other complications in HIV-infected women 1
• However, women with advanced HIV disease may be at increased risk of pelvic infection and should use alternative contraceptive methods until their immunologic and clinical status improves with cART 1

From the Research

Mirena Intrauterine Device Duration

• The Mirena intrauterine device (IUD) is a levonorgestrel-releasing IUD that is approved for use up to 7 years 2.
• However, studies have shown that the Mirena IUD can be effective for up to 8 years, with a cumulative failure rate of 0.68% for years 6-8 3, 4.
• One study found that the Mirena IUD maintained high contraceptive efficacy, user satisfaction, and a favorable safety profile through 8 years of use 3.
• The Society of Family Planning recommends discussing extended use of long-acting reversible contraception, including the Mirena IUD, with patients to allow them to make informed decisions about their reproductive goals and clinical needs 5.
• Key findings on the duration of Mirena IUD use include:
  • Extended use up to 8 years is supported by clinical trials 3, 4.
  • The cumulative failure rate for years 6-8 is 0.68% 3, 4.
  • Patient satisfaction and safety profiles remain favorable through 8 years of use 3.