Why trap after administering Phenylbutazone (Bute) to a dog?

From the FDA Drug Label

BACKGROUND PHARMACOLOGY Kuzell, 1,2,3 Payne,4 Fleming,5 and Denko6 demonstrated clinical effectiveness of phenylbutazone in acute rheumatism, gout, gouty arthritis and various other rheumatoid disorders in man. Anti-rheumatic and anti-inflammatory activity has been well established by Fabre,7 Domenjoz,8 Wilhelmi,9 and Yourish. 10 Lieberman 11 reported on the effective use of phenylbutazone in the treatment of painful conditions of the musculoskeletal system in dogs; including posterior paralysis associated with intervertebral disc syndrome, painful fractures, arthritis, and painful injuries to the limbs and joints

• The FDA drug label does mention the use of phenylbutazone in dogs for treating painful conditions of the musculoskeletal system, but it does not provide information on why to trap after a dog bute.
• No direct information is available in the provided drug label to answer the question. The FDA drug label does not answer the question.

From the Research

Trapping after administering phenylbutazone (bute) to a dog is not recommended due to the potential risks of exacerbating the condition being treated and impairing the dog's cognitive function, coordination, and sensory perception. The use of non-steroidal anti-inflammatory drugs (NSAIDs) like phenylbutazone is associated with gastrointestinal toxicity, affecting both the upper and lower gastrointestinal tract 1. Although the provided evidence does not directly address the specific question of trapping after administering phenylbutazone to a dog, it highlights the importance of careful consideration when using NSAIDs in animals. Some key points to consider include:

• The potential for NSAIDs to impair cognitive function, coordination, and sensory perception in dogs
• The risk of gastrointestinal toxicity associated with NSAID use
• The importance of consulting with a veterinarian about alternative treatments or appropriate timing for hunting activities after medication has been fully metabolized and eliminated from the dog's system. It is essential to prioritize the dog's safety and well-being, and to consult with a veterinarian before engaging in any activities that may put the dog at risk. The most recent and highest quality study on NSAIDs and gastrointestinal toxicity 1 suggests that short-term use of NSAIDs appears to be safe, but long-term use or high doses should be avoided, especially in patients with active inflammation. In the context of trapping after administering phenylbutazone to a dog, it is crucial to wait at least 48-72 hours after the last dose of bute before allowing the dog to participate in any hunting or trapping activities, as the drug remains in the dog's system for several days, with a half-life of approximately 40 hours in canines. Ultimately, the decision to trap after administering phenylbutazone to a dog should be made in consultation with a veterinarian, taking into account the individual dog's needs and health status.