What are Brain-Computer Interfaces (BCIs)?

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From the Guidelines

Brain computer interfaces (BCIs) are systems that enable people to control devices with their thoughts by translating neural activity into commands. These interfaces have the potential to significantly improve the quality of life for individuals with severe motor disabilities or paralysis by providing them with a means of communication and control over their environment. According to the most recent guidelines, there is insufficient evidence to recommend for or against the use of non-invasive brain-computer interfaces to improve upper extremity motor outcomes and activities of daily living 1. However, the technology behind BCIs is rapidly evolving, with advancements in signal processing, machine learning techniques, and component miniaturization potentially leading to more widespread applications in rehabilitation and human-computer interaction. Key aspects of BCIs include:

  • The use of electroencephalography (EEG), electrocorticography (ECoG), or invasive microelectrode arrays to detect brain signals
  • The interpretation of these signals using sophisticated algorithms to identify patterns associated with specific thoughts or intended movements
  • The potential to help people with paralysis, locked-in syndrome, or severe motor disabilities regain communication abilities and control over their environment While the current evidence may not strongly support the use of BCIs for specific outcomes, the potential benefits of this technology in improving morbidity, mortality, and quality of life make it an area of significant interest and ongoing research.

From the Research

Definition and Purpose of Brain Computer Interfaces

  • A brain-computer interface (BCI) is a hardware and software communications system that permits cerebral activity alone to control computers or external devices 2.
  • The primary goal of BCI research is to provide communications capabilities to severely disabled people who are totally paralyzed or 'locked in' by neurological neuromuscular disorders, such as amyotrophic lateral sclerosis, brain stem stroke, or spinal cord injury 2, 3.

Components and Functionality of BCIs

  • A standard BCI consists of several steps, including signal acquisition, preprocessing or signal enhancement, feature extraction, classification, and the control interface 2.
  • BCIs can be invasive or non-invasive, using various technologies such as electroencephalography (EEG), functional near-infrared spectroscopy (fNIRS), or electrocorticography (ECoG) to record brain activity 2, 4, 5.
  • The recorded brain activity is then translated into commands that operate a computer or other device, allowing users to communicate or control external devices 2, 6.

Applications and Benefits of BCIs

  • BCIs have the potential to improve the lives of individuals with severe disabilities, such as those with amyotrophic lateral sclerosis (ALS), by providing a means of communication and control 3, 6.
  • BCIs can also be used to restore movement in individuals with paralysis or other motor disorders, and may augment rehabilitation protocols aimed at restoring useful motor function 6, 5.
  • Recent studies have demonstrated the feasibility of BCIs in enhancing communication for people with later-stage ALS, particularly those in the locked-in state (LIS) or completely locked-in state (CLIS) 3, 4.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Brain computer interfaces, a review.

Sensors (Basel, Switzerland), 2012

Research

Enhancing Communication for People in Late-Stage ALS Using an fNIRS-Based BCI System.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2020

Research

Brain-computer interface in paralysis.

Current opinion in neurology, 2008

Research

Brain-computer interfaces.

Handbook of clinical neurology, 2013

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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