What is the duration of musculoskeletal (MSK) chest pain?

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Last updated: February 18, 2025View editorial policy

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From the Guidelines

Duration of Musculoskeletal Chest Pain

Musculoskeletal (MSK) chest pain can last anywhere from a few days to several weeks, with most cases resolving on their own within 1-3 weeks 1. However, in some cases, it can persist for 6-12 weeks or even longer if underlying conditions such as fibromyalgia or chronic muscle strain are present.

Key Characteristics of MSK Chest Pain

  • Frequency and Duration: More than half of patients experience chronic symptoms lasting >6 months 1.
  • Pain Description: Patients often describe their chest wall symptoms as stinging or pressing, retrosternal or left-sided, occurring more than once daily 1.

Management of Acute MSK Chest Pain

For acute MSK chest pain, the following management strategies can be considered:

  • Over-the-counter pain medications: Acetaminophen (650-1000mg every 4-6 hours) or ibuprofen (400-800mg every 6-8 hours) can be used for 1-2 weeks to manage symptoms 1.
  • Muscle relaxants: A short course of muscle relaxants like cyclobenzaprine (5-10mg at bedtime) for 3-7 days can be considered if pain persists.
  • Non-pharmacologic interventions: Topical nonsteroidal anti-inflammatory drugs (NSAIDs) with or without menthol gel, specific acupressure, or transcutaneous electrical nerve stimulation can be used to reduce pain and improve physical function 1.

Important Considerations

It's essential to note that if MSK chest pain is severe, worsening, or accompanied by other concerning symptoms like difficulty breathing, chest tightness, or radiating pain, immediate medical attention is necessary to rule out more serious conditions.

From the FDA Drug Label

Cyclobenzaprine hydrochloride tablets should be used only for short periods (up to two or three weeks) because adequate evidence of effectiveness for more prolonged use is not available and because muscle spasm associated with acute, painful musculoskeletal conditions is generally of short duration The duration of musculoskeletal (MSK) chest pain is generally of short duration.

  • The exact duration is not specified, but it is implied to be up to two or three weeks based on the recommended treatment period with cyclobenzaprine hydrochloride tablets 2.

From the Research

Duration of Musculoskeletal Chest Pain

The duration of musculoskeletal (MSK) chest pain is not explicitly stated in the provided studies. However, the following points can be noted:

  • The studies focus on the diagnosis, management, and treatment of MSK chest pain, but do not provide specific information on the duration of the condition 3, 4, 5, 6, 7.
  • The management strategies for MSK chest pain include manual therapy, analgesia, and anti-inflammatory agents, which suggest that the condition can be treated and managed, but the duration of treatment is not specified 3, 5, 7.
  • The studies emphasize the importance of careful history taking, physical examination, and diagnostic tests to rule out non-musculoskeletal causes of chest pain, but do not provide information on the duration of MSK chest pain 3, 4, 5, 7.

Key Points

  • MSK chest pain is a common condition that can be caused by various factors, including costochondritis, trauma, and fibromyalgia 4, 5.
  • The diagnosis of MSK chest pain is typically made through a combination of history taking, physical examination, and diagnostic tests 3, 4, 5, 7.
  • Treatment options for MSK chest pain include manual therapy, analgesia, and anti-inflammatory agents, as well as physiotherapeutic and physical treatment measures 3, 5, 6, 7.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Musculoskeletal causes of chest pain.

Australian family physician, 2001

Research

[Musculoskeletal-related chest pain].

Der Internist, 2017

Research

Musculoskeletal chest wall pain.

Australian family physician, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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